Pregabalin Impurity 5
3-Isobutyl glutarimide
CAS: 916982-10-0
Molecular Formula: C9H15NO2
Pregabalin Impurity 5 - Names and Identifiers
Pregabalin Impurity 5 - Physico-chemical Properties
| Molecular Formula | C9H15NO2 |
| Molar Mass | 169.22 |
| Density | 1.016 |
| Melting Point | 136-138℃ |
| Boling Point | 305℃ |
| Flash Point | 131℃ |
| Solubility | Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 11.78±0.40(Predicted) |
| Storage Condition | Refrigerator |
Pregabalin Impurity 5 - Introduction
3-Isobutyl glutarimide is an organic compound with the chemical formula C9H17NO2, which is a yellow to brown crystal or solid.
Nature:
-Appearance: Yellow to brown crystal or solid
-Melting point: about 95-98°C
-Boiling point: approximately 334°C
-Solubility: Soluble in hot alcohols, ketones and acids, slightly soluble in water
Use:
- 3-Isobutyl glutarimide can be used as inhibitors, melting point depressants and expandable reference substances
-In chemical research, it can be used as an intermediate and reagent for organic synthesis
-Can be used as an additive in the preparation of certain polymers and polyamide materials
Method:
3-Isobutyl glutarimide can generally be prepared by the following steps:
1. React glutarimide and isobutanol in a round bottom flask
2. Heat and stir at an appropriate temperature
3. distillation and rectification of the reaction mixture to obtain the target product 3-Isoputyl glutarimide
Safety Information:
- 3-Isobutyl glutarimide may be irritating and corrosive to the eyes and skin, and should be rinsed with water immediately upon contact.
-When used in the workplace, appropriate protective measures should be taken, such as wearing protective gloves, glasses and or respirators.
-Store away from fire and oxidizing agents, and keep the container tightly closed.
Nature:
-Appearance: Yellow to brown crystal or solid
-Melting point: about 95-98°C
-Boiling point: approximately 334°C
-Solubility: Soluble in hot alcohols, ketones and acids, slightly soluble in water
Use:
- 3-Isobutyl glutarimide can be used as inhibitors, melting point depressants and expandable reference substances
-In chemical research, it can be used as an intermediate and reagent for organic synthesis
-Can be used as an additive in the preparation of certain polymers and polyamide materials
Method:
3-Isobutyl glutarimide can generally be prepared by the following steps:
1. React glutarimide and isobutanol in a round bottom flask
2. Heat and stir at an appropriate temperature
3. distillation and rectification of the reaction mixture to obtain the target product 3-Isoputyl glutarimide
Safety Information:
- 3-Isobutyl glutarimide may be irritating and corrosive to the eyes and skin, and should be rinsed with water immediately upon contact.
-When used in the workplace, appropriate protective measures should be taken, such as wearing protective gloves, glasses and or respirators.
-Store away from fire and oxidizing agents, and keep the container tightly closed.
Last Update：2024-04-10 22:29:15
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View History
Pregabalin Impurity 5
2 - (1H -苯并[E]咪唑-2基)苯胺
1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-olhydrochlorid
N-ETHYL-N-(2-METHYLPROP-2-ENYL)PIPERAZINE-1-SULFONAMIDE
(Z)-2-HYDROXYIMINO-2-(2-AMINOTHIAZOL-4-YL)ACETIC ACID
Methyl 4-(3-{[(3-Methoxy-5-Methylpyrazin-2-yl)[(2-Methylpropoxy)carbonyl]aMino]sulfonyl}pyridin-2-yl)benzoate
5-CLORO-2-ADAMANTONE
2 - (1H -苯并[E]咪唑-2基)苯胺
1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-olhydrochlorid
N-ETHYL-N-(2-METHYLPROP-2-ENYL)PIPERAZINE-1-SULFONAMIDE
(Z)-2-HYDROXYIMINO-2-(2-AMINOTHIAZOL-4-YL)ACETIC ACID
Methyl 4-(3-{[(3-Methoxy-5-Methylpyrazin-2-yl)[(2-Methylpropoxy)carbonyl]aMino]sulfonyl}pyridin-2-yl)benzoate
5-CLORO-2-ADAMANTONE